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If you are at all unsure of the suitability of an investment for your circumstances please contact us for personal advice.The HL Select UK Shares Fund is managed by our sister company HL Fund Managers Ltd.To provide access without cookies would require the site to create a new session for every page you visit, which slows the system down to an unacceptable level.This site stores nothing other than an automatically generated session ID in the cookie; no other information is captured.

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It is not a personal recommendation to invest in a particular company.Thus, if a study of an unapproved drug product is completed after January 18, 2017, then the study results would need to be submitted no later than one year after the primary completion date unless the submission deadline is delayed or waived, as discussed below.As noted above, the standard submission deadline for reporting clinical trial results data for all applicable clinical trials is one year after the primary completion date of the clinical trial.There are many reasons why a cookie could not be set correctly.Below are the most common reasons: This site uses cookies to improve performance by remembering that you are logged in when you go from page to page.* This is the combined weighting of holdings that we are actively trading.When we are active in the market we won't announce the position until trading is complete to give us the best chance of obtaining good prices for our trading activity.HHS determined that submission of results of applicable clinical trials for investigational medical products that are not commercially available furthers the statutory purpose of the database “to provide more complete results information and to enhance patient access to and understanding of the results of clinical trials.” 81 Fed. The following discussion provides a brief overview of the new results posting requirements and the transition rules in place for studies completed before and after the effective date of the regulation.approved, licensed, or cleared by FDA, the results information must be submitted in accordance with 42 CFR 11.48 if the primary completion date is on or after the effective date of the rule. Note that the “primary completion date” refers to the date that the final subject was examined or received an intervention for the purposes of final collection of data for the primary outcome. The general categories of data required for submission under 42 CFR 11.48 include: (1) participant flow, (2) demographic and baseline characteristics, (3) outcomes and statistical analyses, (4) adverse event information, (5) protocol and statistical analysis plan, (6) administrative information, and (7) additional results information for applicable device clinical trials of unapproved or uncleared devices.Allowing a website to create a cookie does not give that or any other site access to the rest of your computer, and only the site that created the cookie can read it.On 31 December, the Russian President signed into Federal Law No.