Sedating antihistamines wiki

26 Sep

In the event of an overdose or if combined with another sedative, many of these drugs can cause unconsciousness (see hypnotic) and even death.

There is some overlap between the terms "sedative" and "hypnotic".

DXM manifests its effects in a series of plateaus, with dose determining which plateau (and consequently which effects) one will experience.

Lower dose plateaus can be well suited to relaxation, light social interaction and listening to music, while higher doses result in a more encompassing dissociative experience which does not lend itself to attentive social attention.

The high is not for everyone; it is said to loosely follow the rule of thirds: one third hates it, one third doesn't care, and one third like it.

It should not be underestimated as a hallucinogenic, at higher dosages it mimics high doses of ketamine but with more psychedelic properties.

Rupatadine discovery, pre-clinical and clinical development was performed by J. It was launched in 2003 in Spain under the brand name of Rupafin.

Although sedatives do not relieve pain in themselves, they can be a useful adjunct to analgesics in preparing patients for surgery, and are commonly given to patients before they are anaesthetized, or before other highly uncomfortable and invasive procedures like cardiac catheterization, colonoscopy or MRI.If you are on a personal connection, like at home, you can run an anti-virus scan on your device to make sure it is not infected with malware.If you are at an office or shared network, you can ask the network administrator to run a scan across the network looking for misconfigured or infected devices.Doses of sedatives such as benzodiazepines, when used as a hypnotic to induce sleep, tend to be higher than amounts used to relieve anxiety, whereas only low doses are needed to provide a peaceful effect.Sedatives can be misused to produce an overly-calming effect (alcohol being the classic and most common sedating drug).Dependent users may get withdrawal symptoms ranging from restlessness and insomnia to convulsions and death.Dextromethorphan (also known as 'DXM', 'DM' or 'robo') is an over-the-counter antitussive (cough medicine) which, when taken at doses exceeding the recommended therapeutic range, becomes a powerful dissociative drug with psychedelic properties.Its mechanisms of action are multiple, including action as a nonselective A monoamine neurotransmitter, biochemically derived from tryptophan, that is primarily found in the gastrointestinal (GI) tract, platelets, and central nervous system (CNS) of humans and animals.Diphenhydramine (DPH, also sold as Benadryl) is an antihistamine with anticholinergic and sedative effects.Brand names include Rupafin, Alergoliber, Rinialer, Pafinur, Rupax, Urtimed and Ralif, among others.At higher doses it may result in slurred speech, staggering gait, poor judgment, and slow, uncertain reflexes.